论文
Mutability Landscapes-Guided Engineering of L-Threonine Aldolase Revealing the Prelog Rule in Mediating Diastereoselectivity of C-C Bond Formation.
期刊: Angewandte Chemie International Edition 2022作者: Haoran Yu* And Jianping Wu*,Lirong Yang,Gang Xu,Lanxin Xiao,Zhongji Pu,Wenlong Zheng
DOI:10.1002/anie.202213855
Substrate access path-guided engineering of L-threonine aldolase for improving diastereoselectivity
期刊: Chemical Communications 2022作者: And Jianping Wu*,Lirong Yang,Gang Xu,Xiuli Cheng,Zhe Wang,Kaitong Chen,Wenlong Zheng
DOI:10.1039/D2CC02644A
Directed Evolution of L‑Threonine Aldolase for the Diastereoselective Synthesis of β‑Hydroxy-α-amino Acids
期刊: ACS catalysis 2021作者: And Jianping Wu*,Lirong Yang,Gang Xu,Xiuli Cheng,Zhe Wang,Kaitong Chen,Sai Fang,Haoran Yu,Wenlong Zheng
Construction and Application of PLP Self-Sufficient Biocatalysis System for Threonine Aldolase
期刊: Enzyme and Microbial Technology 2020作者: Jianping Wu,Lirong Yang,Gang Xu,Xiuli Cheng,Sai Fang,Kaitong Chen,Wenlong Zheng
Construction of a highly diastereoselective aldol reaction system with l-threonine aldolase by computer-assisted rational molecular modification and medium engineering
期刊: Organic Letters 2020作者: And Jianping Wu*,Lirong Yang,Gang Xu,Xiuli Cheng,Zhe Wang,Kaitong Chen,Wenlong Zheng
