简历详情

A mitochondrion-targeting two-photon photosensitizer with aggregation-induced emission characteristics for hypoxia-tolerant photodynamic therapy

期刊: Chemical Engineering Journal  2022
作者: Ben Zhong Tang,Gaixia Xu,Dong Wang,Ken-Tye Yong,Wing-Cheung Law,Chengbin Yang,Jianyu Zhang,Zhengzheng Li,Miaozhuang Fan,Shuo Tang,Zhijun Zhang,Zhourui Xu,Wei Zhu,Yihang Jiang
DOI:10.1016/j.cej.2022.137604

Fabry-Perot Interferometer Based on a Fiber-Tip Fixed-Supported Bridge for Fast Glucose Concentration Measurement

Blood glucose concentration is important for metabolic homeostasis in humans and animals. Many diabetic patients need to detect blood glucose daily which burdens community hospitals and family healthcare. Optical fiber sensors are widely used in biomedical detection because of their compact structure, fast response, high sensitivity, low cost, and ease of operation. In this work, we constructed a Fabry-Perot (FP) cavity biosensor for the fast detection of glucose concentration in serum. The femtosecond laser micromachining was applied to fabricate the FP cavity by printing the fiber-tip fixed-supported bridge at the end face of the optical fiber. An additional hemisphere was printed at the center of the outer surface of the bridge to avoid multi-beam interference. The results demonstrated that the proposed biosensor had high refractive index (RI) detection sensitivity, roughly 1039 nm/RIU at a wavelength of 1590 nm, and the detection sensitivity for glucose was around 0.185 nm/ (mg/mL) at a wavelength of 1590 nm. Due to its high sensitivity, compact structure, and fast response, the FP cavity biosensor has great potential to be applied in family healthcare for glucose concentration detection of diabetic patients.

期刊: Biosensors  2022
作者: Gaixia Xu,Changrui Liao,Yiping Wang,Biqin Dong,Xiaomei Wang,Chengbin Yang,Zhourui Xu,Ribao Chen,Yihang Jiang,Cong Zhao,Mengqiang Zou,Shuo Tang
DOI:10.3390/bios12060391