Xia Lab-Radical Mass Spectrometry

3. Advances of PB-MS/MS by other research groups around the world.(2017-2021)

31. Liu, Z.; S. Rochfort*; Regio-distribution and double bond locations of unsaturated fatty acids in phospholipids of bovine milk. Food Chemistry, 2021, Available online 2 November.


30. Deng, J.; Yang, Y.*; Zeng, Z.; Xiao, X.; Li, J.; Luan, T.*; Discovery of Potential Lipid Biomarkers for Human Colorectal Cancer by In-Capillary Extraction Nanoelectrospray Ionization Mass Spectrometry. Analytical Chemistry, 2021, 93, 38, 13089–13098


29. Zhang, J.; Guo, C.; Huo, X.; Ma, X.; Li, X.; Zeper, A.; Chu, Y.; Wang, X.; Tang, F.; Unsaturated lipid isomeric imaging based on the Paternò–Büchi reaction in the solid phase in ambient conditions. Talanta, 2021, 235, 122816.


28. Sun, C; Ma, C; Li, L; Han, Y; Wang, D; Wan,X; "A novel on-tissue cycloaddition reagent for mass spectrometry imaging of lipid C=C position isomers in biological tissues", Chinese Chemical Letters, 2021, Available online 12 August.


27. Huang, W.; Zhou. H.; Yuan, M.; Lan, L.; Hou, A.; Ji, S. Comprehensive Characterization of the Chemical Constituents in Platycodon Grandiflorum by an Integrated Liquid Chromatography-Mass Spectrometry Strategy. Journal of Chromatography A, 2021, 1654, 462-477.


26. Yang Y. Coupling Paternò-Büchi Reaction with Ambient NanoESI-MS for Identification of Unsaturated Triacylglycerols in Peanut Oils. Journal of Chinese Mass Spectrometry Society, 2021, 42(4): 455-461.


25. Wang, D.; Park, H.; Wang, Z.; Lacombe, R.S.; Shmanai, V.V.; Bekish, A.V.; Schmidt, K.; Shchepinov, M.S.; Brenna, J.T.“Toward Quantitative Sequencing of Deuteration of Unsaturated Hydrocarbon Chains in Fatty Acids" Analytical Chemistry, 2021, 93, 8238–8247


24. Xu, S.; Lv, X.; Wu, B.; Xie, Y.; Wu, Z.; Tu, X.; Chen, H.; Wei, F. Pseudotargeted Lipidomics Strategy Enabling Comprehensive Profiling and Precise Lipid Structural Elucidation of Polyunsaturated Lipid-Rich Echium Oil. Journal of Agricultural and Food Chemistry, 2021


23. Wäldchen, F.; Mohr, F.; Wagner, A.H.; Heiles, S. "Multifunctional reactive MALDI matrix enabling high-lateral resolution dual polarity MS imaging and lipid C= C position-resolved MS2 imaging." Analytical Chemistry. 2020, 92, 14130–14138


22. Jeck, V.; Froning, M.; Tiso, T.; Blank, L. M.; Hayen, H. "Double bond localization in unsaturated rhamnolipid precursors 3-(3-hydroxyalkanoyloxy) alkanoic acids by liquid chromatography–mass spectrometry applying online Paternò–Büchi reaction." Analytical and bioanalytical chemistry, 2020, 412, 5601-5613.


21.Maddox, S. W., Olsen, S. S., Velosa, D. C., Burkus-Matesevac, A., Peverati, R., & Chouinard, C. D. Improved Identification of Isomeric Steroids using the Paternò-Büchi Reaction with Ion Mobility-Mass Spectrometry. Journal of the American Society for Mass Spectrometry, 2020, 31, 2086–2092


20. Xu, S.; Wei, F.; Xie, Y.; Wu, B.; Lv, X.; Qin, Z.; Chen, H. Localisation of C=C Bond and Absolute Quantification of Unsaturated Fatty Acids in Vegetable Oils based on Photochemical Derivatisation Reaction Coupled with Mass Spectrometry. International Journal of Food Science & Technology, 2020, 55,  2883-2892


19. Li, P.; Deng, J.; Xiao, N.; Cai, X.; Wu, Q.; Lu, Z.; Du, B. "Identification of polyunsaturated triacylglycerols and CC location isomers in sacha inchi oil by photochemical reaction mass spectrometry combined with nuclear magnetic resonance spectroscopy." Food chemistry, 2020, 307, 125568.


18. Zhu, Y.; Wang, W.; Yang, Z. "Combining Mass Spectrometry with Paternò-Büchi Reaction to Determine Double-bond Positions in Lipids at the Single-cell Level." Analytical Chemistry, 2020, 92, 11380–11387


17. Xu, S.; Wu, B.; Oresic, M.; Xie, Y.; Yao, P.; Wu, Z.; Wei, F. "Double Derivatization Strategy for High-Sensitivity and High-Coverage Localization of Double Bonds in Free Fatty Acids by Mass Spectrometry." Analytical Chemistry, 2020, 92, 6446-6455.


16. Feng, G.; Hao, Y.; Wu, L.; Chen, S. "A visible-light activated [2+ 2] cycloaddition reaction enables pinpointing carbon–carbon double bonds in lipids." Chemical Science, 2020, 11, 7244-7251.


15. Esch, P.; Heiles, S. "Investigating C=C Positions and Hydroxylation Sites in Lipids Using Paternò–Büchi Functionalization Mass Spectrometry." Analyst, 2020, 145, 2256-2266.


14. Wäldchen, F.; Spengler, B.; Heiles, S. "Reactive Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Using an Intrinsically Photoreactive Paternò–Büchi Matrix for Double-Bond Localization in Isomeric Phospholipids." Journal of the American Chemical Society, 2019, 141, 11816-11820.


13. Deng, J.; Yang, Y.; Liu, Y.; Fang, L.; Lin, L.; Luan, T. "Coupling Paternò-Büchi Reaction with Surface-Coated Probe Nanoelectrospray Ionization Mass Spectrometry for In Vivo and Microscale Profiling of Lipid C═ C Location Isomers in Complex Biological Tissues." Analytical chemistry, 2019, 91, 4592-4599.


12. Esch, P.; Fischer, M.; Heiles, S.; Schäfer, M. "Olefinic Reagents Tested for Peptide Derivatization with Switchable Properties: Stable upon Collision Induced Dissociation and Cleavable by In-Source Paternò-Büchi Reactions." Journal of Mass Spectrometry, 2019, 54, 976-986.


11. Birk, F.; Fraatz, M. A.; Esch, P.; Heiles, S.; Pelzer, R.; Zorn, H. "Industrial Riboflavin Fermentation Broths Represent a Diverse Source of Natural Saturated and Unsaturated Lactones." Journal of Agricultural and Food Chemistry, 2019, 67, 13460-13469.


10. Zhao, X.; Chen, J.; Zhang, W.; Yang, C.; Ma, X.; Zhang, S.; Zhang, X. "Lipid Alterations during Zebrafish Embryogenesis Revealed by Dynamic Mass Spectrometry Profiling with C=C Specificity." Journal of The American Society for Mass Spectrometry, 2019, 30, 2646-2654.


9. Bednařík, A.; Bölsker, S.; Soltwisch, J.; Dreisewerd, K., "An On-Tissue Paternò–Büchi Reaction for Localization of Carbon–Carbon Double Bonds in Phospholipids and Glycolipids by Matrix-Assisted Laser-Desorption–Ionization Mass-Spectrometry Imaging." Angewandte Chemie International Edition, 2018, 57, 12092-12096.


8. Jeck, V.; Korf, A.; Vosse, C.; Hayen, H. "Localization of Double-Bond Positions in Lipids by Tandem Mass Spectrometry Succeeding High-Performance Liquid Chromatography with Post-Column Derivatization." Rapid Communications in Mass Spectrometry, 2019, 33, 86-94.


7. Bechtella, L.; Kirschbaum, C.; Cosset, M.; Clodic, G.; Matheron, L.; Bolbach, G.; Sagan, S.; Walrant, A.; Sachon, E. "Benzophenone Photoreactivity in a Lipid Bilayer To Probe Peptide/Membrane Interactions: Simple System, Complex Information." Analytical Chemistry, 2019, 91, 9102-9110.


6. Korf, A.; Jeck, V.; Schmid, R.; Helmer, P. O.; Hayen, H. "Lipid Species Annotation at Double Bond Position Level with Custom Databases by Extension of the MZmine 2 Open-Source Software Package." Analytical Chemistry, 2019, 91, 5098-5105.


5. Xu, T.; Pi, Z.; Song, F.; Liu, S.; Liu, Z. "Benzophenone used as the photochemical reagent for pinpointing C= C locations in unsaturated lipids through shotgun and liquid chromatography-mass spectrometry approaches." Analytica chimica acta, 2018, 1028, 32-44.


4. Esch, P.; Heiles, S. "Charging and Charge Switching of Unsaturated Lipids and Apolar Compounds Using Paternò-Büchi Reactions." Journal of the American Society for Mass Spectrometry, 2018, 29, 1971-1980.


3. Wäldchen, F.; Becher, S.; Esch, P.; Kompauer, M.; Heiles, S. "Selective Phosphatidylcholine Double Bond Fragmentation and Localisation Using Paternò–Büchi Reactions and Ultraviolet Photodissociation." Analyst, 2017, 142, 4744-4755.


2. Murphy, R. C.; Okuno, T.; Johnson, C. A.; Barkley, R. M. "Determination of double bond positions in polyunsaturated fatty acids using the photochemical Paterno-Buchi reaction with acetone and tandem mass spectrometry." Analytical Chemistry, 2017, 89, 8545-8553.


1. Jiang, X.; Wang, J.; Guan, Q.; Hu, J.; Xu, J.; Chen, H. "Identification of C=C Location of Unsaturated Phosphatidylcholines in Cell by Photochemical Reaction-Tandem Mass Spectrometry." Chinese Journal of Analytical Chemistry, 2017, 45, 1988-1995.



Created: Jul 29, 2020 | 14:22