卢培龙实验室 - 蛋白质设计
分享到
Three-dimensional structure of human γ-secretase
14.08.2014
The γ-secretase complex, comprising presenilin 1 (PS1), PEN-2, APH-1 and nicastrin, is a membrane-embedded protease that controls a number of important cellular functions through substrate cleavage. Aberrant cleavage of the amyloid precursor protein (APP) results in aggregation of amyl...
