By combining high-throughput screening and sequencing, we aim to study mechanisms underlying cancer metastasis and drug resistance with systematic identification and analysis of critical mutations. We also seek to identify host factors involved in pathogen infection.

结合高通量基因组编辑、高通量测序等技术手段，对影响癌症发生、发展及转移的关键基因突变进行鉴定和功能性分析，并对癌症的耐药机制、合成致死进行研究。同时探索病原微生物感染的关键宿主因子。