This is a wonderful opportunity for translational research bridge clinic and basic science. We have been focusing on an interesting research field: regulation of stem cell and cancer development by perineural niche in the epithelium tissues (skin and stomach). More important, as a research lab in the affiliated hospital of the Medical School in Zhejiang University-Sir Run Run Shaw hospital, we took the advantage of clinic and studies are closely related with diseases. The mission of the lab is to find the underline mechanism of how neuronal system crosstalk with epithelium tissues and affect diseases.