研究方向:

    主要研究领域包括高分子和生物膜物理，尤其是在基因表达和调控、穿膜输运等生命活动过程中涌现出来的物理规律。

    近期的工作主要集中于：

    1. 基因组三维结构、演化及功能。

    2. 溶液环境、空间受限对高分子体系的影响。

    3. 大分子与细胞膜的相互作用和药物输运机制。

    4. 纳米材料与生物系统的相互作用、纳米毒性

研究人员：

教师：刘磊、胡娟梅

研究生：谈彬彬、曹欣萌、时晨

近期代表性论文：

1. Extracting multi-way chromatin contacts from Hi-C data
Lei Liu, Bokai Zhang, and Changbong Hyeon
PLoS Comput. Biol. 17, e1009669 (2021)

2. Revisiting the organization of Polycomb-repressed domains: 3D chromatin models from Hi-C compared with super-resolution imaging
Lei Liu, and Changbong Hyeon
Nucleic Acids Res. 48, 11486-11494 (2020)

3. Compressing Θ-chain in Slit Geometry
Lei Liu, Philip A. Pincus, and Changbong Hyeon
Nano Lett. 19, 5667-5673 (2019)

4. Chain organization of human interphase chromosome determines the spatiotemporal dynamics of chromatin loci
Lei Liu, Guang Shi, D. Thirumalai, and Changbong Hyeon
PLoS Comput. Biol. 14, e1006617 (2018)

5. Heterogeneous Morphology and Dynamics of Polyelectrolyte Brush Condensates in Trivalent Counterion Solution
Lei Liu, Philip A. Pincus, and Changbong Hyeon
Macromolecules 50, 1579-1588 (2017)

6. Improved Intracellular Delivery of Polyarginine Peptides with Cargoes
Juanmei Hu, Yimin Lou, and Fengmin Wu
J. Phys. Chem. B 123, 2636-2644 (2019)

7. Computational Investigations of Arginine‐Rich Peptides Interacting with Lipid Membranes 
Juanmei Hu, Wen-de Tian, and Yu-qiang Ma
Macromol. Theory Simul., 24, 399-406 (2015)

8. The self-assembly of linear-dendritic and lipid-like copolymers investigated by computer simulations
Juanmei Hu, Wen-de Tian, and Yu-qiang Ma
RSC Adv., 4, 59785-59791 (2014)