We are developing variety of high-throughput screening platforms based on genome editing technology, to facilitate the functional identification of coding/non-coding genes, regulatory elements, and critical domains/sequences.
将基因组编辑技术应用于高通量功能基因组学研究，建立全基因组编码及非编码区的高通量功能性筛选平台以及功能性位点扫描技术，对高等生物的编码/非编码基因、表达调控元件等进行功能性研究，从系统生物学的角度发现新的关键序列及机制。
创建: Apr 11, 2018 | 21:31
By combining high-throughput screening and sequencing, we aim to study mechanisms underlying cancer metastasis and drug resistance with systematic identification and analysis of critical mutations. We also seek to identify host factors involved in pathogen infection.
结合高通量基因组编辑、高通量测序等技术手段，对影响癌症发生、发展及转移的关键基因突变进行鉴定和功能性分析，并对癌症的耐药机制、合成致死进行研究。同时探索病原微生物感染的关键宿主因子。
创建: Apr 11, 2018 | 21:30
